Castle Biosciences, Inc. (CSTL)

Nasdaq · Healthcare · Diagnostics & Research

$36.65+3.07%as of Oct 6, 2026, 1:35 AM ET

Market cap
$1.1B
52-week range
$17.72 – $44.28
52-week change
+55.15%
EPS (trailing)
−$0.64
Analyst rating
1.0 Strong buy
Next earnings
Nov 2, 2026

Fiscal year to Dec 2025

Revenue
$344M (+3.66%)
Net income
−$24.2M
Operating margin
−12.4%
Diluted EPS
−$0.83
Free cash flow
$28.3M

From the company’s annual report on SEC EDGAR.

About Castle Biosciences, Inc.

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma.

Headquarters: Friendswood, United States · 1,002 employees · castlebiosciences.com