Krystal Biotech, Inc. (KRYS)

Nasdaq · Healthcare · Biotechnology

$334.85+3.90%as of Oct 6, 2026, 1:35 AM ET

Market cap
$9.9B
P/E (trailing)
42.0
Forward P/E
35.9
52-week range
$179.19 – $382.54
52-week change
+76.09%
EPS (trailing)
$7.98
Analyst rating
1.3 Strong buy
Next earnings
Nov 2, 2026

Fiscal year to Dec 2025

Revenue
$389M (+33.95%)
Net income
$205M
Operating margin
41.4%
Diluted EPS
$6.84
Free cash flow
$189M

From the company’s annual report on SEC EDGAR.

About Krystal Biotech, Inc.

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.

Headquarters: Pittsburgh, United States · 295 employees · krystalbio.com