Axsome Therapeutics, Inc. (AXSM)

Nasdaq · Healthcare · Biotechnology

$177.08−1.21%as of Oct 6, 2026, 4:35 AM ET

Market cap
$9.3B
Forward P/E
37.5
52-week range
$117.30 – $260.19
52-week change
+51.09%
EPS (trailing)
−$3.74
Analyst rating
1.2 Strong buy
Next earnings
Nov 2, 2026

Fiscal year to Dec 2025

Revenue
$639M (+65.55%)
Net income
−$183M
Operating margin
−26.1%
Diluted EPS
−$3.68
Free cash flow
−$93.9M

From the company’s annual report on SEC EDGAR.

About Axsome Therapeutics, Inc.

Axsome Therapeutics, Inc., a biopharmaceutical company, develops and delivers novel therapies for the management of central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist, sigma-1 receptor agonist, aminoketone, and CYP2D6 inhibitor indicated for the treatment of major depressive disorder in adults; Sunosi (solriamfetol), a dopamine and norepinephrine reuptake inhibitor, trace amine-associated receptor 1 agonist, and 5-HT1A agonist indicated for the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea; and Symbravo (MoSEIC meloxicam rizatriptan), or AXS-07, a rapidly absorbed, multi-mechanistic, selective COX-2 inhibitor, and 5-HT1B/1D agonist indicated for the acute treatment of migraine with or without aura.

Headquarters: New York, United States · 1,346 employees · axsome.com