Olema Pharmaceuticals, Inc. (OLMA)
Nasdaq · Healthcare · Biotechnology
$8.25+0.30%as of Oct 6, 2026, 7:35 AM ET
- Market cap
- $722M
- 52-week range
- $6.65 – $36.26
- 52-week change
- −21.22%
- EPS (trailing)
- −$2.12
- Next earnings
- Nov 9, 2026
Fiscal year to Dec 2025
- Net income
- −$162M
- Diluted EPS
- −$1.87
From the company’s annual report on SEC EDGAR.
About Olema Pharmaceuticals, Inc.
Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. The company's lead product candidate is palazestrant, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 3 clinical trial for the treatment of recurrent, locally advanced, or metastatic ER-positive, human epidermal growth factor receptor 2-negative breast cancer; OPERA-01, the pivotal Phase 3 clinical trial of palazestrant as a monotherapy in second/third-line ER+/HER2- metastatic breast cancer; and palazestrant with CDK4/6 inhibitors, a phosphatidylinositol 3 kinase alpha (PI3Ka) inhibitor alpelisib, a mechanistic target of rapamycin inhibitor, and a CDK4 inhibitor that is in Phase 1b/2 clinical trial for the treatment of ER+/HER2- advanced or metastatic breast cancer. It also develops OP-3136, an orally-available small molecule that potently and selectively inhibits KAT6 which is in Phase 1 clinical trials for patients with breast and other solid tumor cancers. The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009.
Headquarters: San Francisco, United States · 150 employees · olema.com