Senti Biosciences Holdings, Inc. (SNTI)

Nasdaq · Healthcare · Biotechnology

$0.3451+7.07%as of Oct 6, 2026, 4:35 AM ET

Market cap
$10.8M
52-week range
$0.29 – $2.88
52-week change
−81.39%
EPS (trailing)
−$1.72

Fiscal year to Dec 2025

Revenue
$22K
Net income
−$61.4M
Operating margin
−312631.8%
Diluted EPS
−$2.73
Free cash flow
−$43.6M

From the company’s annual report on SEC EDGAR.

About Senti Biosciences Holdings, Inc.

Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The company's lead product candidates utilize off-the-shelf healthy adult donor derived natural killer (NK) cells to create CAR-NK cells outfitted with gene circuit technologies in various oncology indications with unmet need. It offers SENTI-202, a logic gated off-the-shelf CAR-NK cell therapy for the treatment of blood cancers and relapsed/refractory hematological malignancies, including acute myeloid leukemia. In addition, the company develops the tumor-associated antigen and protective antigen paired discovery platform to select and validate NOT GATE antigen candidates and identify tumor-associated antigens in cancer cells. Further, its pipeline includes preclinical programs, which comprise a solid tumor cell therapy program; and partnered programs related to cell therapies for regenerative medicines. The company has a strategic collaboration with Celest Therapeutics (Shanghai) Co. Ltd. The company was formerly known as Senti Biosciences, Inc.

Headquarters: South San Francisco, United States · 39 employees · sentibio.com